High molecular weight chitin (chitosamine) can directly activate macrophages and enhance cellular immunity. At the same time, chitosan oligosaccharides can promote the production of interleukin I and the induction of interleukin I, indicating that chitosamine can enhance cellular immunity and Humoral immunity; when the concentration of chitosamine reaches 64mg / L, it can enhance the activity of NK cells in the lymphatic system (natural killer cells, about 4 to 5 times increase); when the concentration of chitosamine reaches 96mg / L, LAK cells (lymphokine) Activated killer cells) are very active.

Chitin can detoxify and detoxify, an important reason is that it has a strong adsorption capacity. First, chitin is a high score The daughter substance is sticky at a certain concentration; secondly, chitin is a linear compound composed of 1000 to 3000 molecules, intertwined with each other.This structure makes a lot of voids inside and a large surface area, so it is expressed by the intermolecular gravity The surface absorption capacity is also strong; more importantly, there are a large number of polar groups-hydroxyl (-OH) and amino (-NH2) in the chitin molecular structure, so the polarity is very strong and can be adsorbed with polarity The form of adsorption of many non-charged polar particles, such as low-density lipoprotein cholesterol, glycerides, etc., and can be eliminated from the body.

Chitin (chitosan) can form polymers with cationic groups in gastric juice, which can eliminate negatively charged ions, such as fatty acid bile acid, lactate chloride, etc. in the form of electrostatic adsorption. Chitin detoxification The second mechanism of detoxification is that the hydroxyl and amino groups contained in its molecules can form chelate with metal ions. Some heavy metal ions such as mercury, lead, cadmium, etc. can enter the body through contaminated water, food air and skin, if accumulated Too much will cause disease. Chitin removes heavy metals through specific adsorption methods. The third mechanism of chitosan detoxification is that it belongs to cellulose. After oral administration, a considerable amount of it will not be decomposed and stay in the intestine. The decomposed chitin has a large molecular weight and is not easy to absorb, so it absorbs a lot of water to increase the intestinal volume, exerts a certain pressure on the intestinal wall, and causes bowel peristalsis to increase and defecation, thereby promoting the elimination of harmful substances in the body.

When the chitosan concentration is 6 mg / L, the bacteriostatic rate against Staphylococcus aureus reaches 100%, and the bacteriostatic rate against Candida albicans reaches 82%; when the concentration reaches 10 mg / L, most The bacteriostatic rate of gram-negative bacteria reaches 60% to 100%. The mechanism of anti-Gram positive bacteria of chitosamine is to adsorb on the cell surface, form a polymer film, prevent the transport of nutrients into the cell, and thus play a bacteriostatic and sterilizing role , The higher the concentration, the denser the film formed, the more obvious the antibacterial effect. The sterilization mechanism for Gram-negative bacteria is that chitosamine enters the bacteria through osmosis, absorbs the cytoplasm with anions, flocculates, and disrupts the normal function of cells , Thereby killing bacteria, the smaller the relative molecular mass, the better the effect.